Tom Baer is the Executive Director of the Stanford Photonics Research Center at Stanford University and co-founder of Arcturus Bioscience, Inc. which he established in 1996. He served as the company's Chairman and CEO until January 2005. Prior to Arcturus, Dr. Baer was Vice President of Research at Biometric Imaging, where he led an interdisciplinary group developing instrumentation and reagents with applications in the areas of AIDS monitoring, bone marrow transplant therapy, and blood supply quality control.
Professor Bao’s research group uses chemical and chemical engineering approaches towards the fabrication of functional nano- and microstructures with novel electronic and photonic properties. Research activities involve organic and polymer synthesis, surface chemistry, nano- and micropatterning, bio-inspired patterning and assembly, and materials and device characterization.
Research in the Block lab marries aspects of physics and biology to study the properties of proteins or nucleic acids at the level of single macromolecules and molecular complexes. Experimental tools include laser-based optical traps (“optical tweezers”) and a variety of state-of-the-art fluorescence techniques, in conjunction with custom-built instrumentation for the nanometer-level detection of displacements and piconewton-level detection of forces. Current experimental work in the lab focuses on measuring the physical properties of biological motors and key polymerase enzymes. The group has recently invented a new method for single molecule sequencing of nucleic acid using laser trapping
Nanoscale electronic and photonic materials and devices, Guiding and manipulation of light in metal-optic structures, Optical properties of semiconductor nanocrystals, Optical sensors for bio-applications. Fundamentals of ion beam modification
Professor Butte's laboratory's goal is to address fundamental and therapeutic questions in immunology using innovative nanotechnological and biophysical approaches to visualize and manipulate cells. Our primary focus is on understanding the molecular controls that balance T cell activation versus tolerance. The ultimate aim of our work is to manipulate T cell signaling pathways to control immunologically-mediated diseases. We apply to in vitro and in vivo systems the techniques of AFM, soft lithography, and confocal microscopy. Projects in the lab include discovery and characterization of new inhibitory pathways of T cells; visualization of single-receptor activity in the T cell immunological synapse; super-resolution microscopy of immune cell receptors; nanoscale manipulation of single-receptors on T cells; atomic force microscopy of cells and biomaterials; development of low-cost diagnostic tools for immune monitoring and autoimmune diseases (such as Type 1 diabetes and multiple sclerosis); mechanobiology of immune cells, cardiomyocytes, and cancer cells; and characterization of self-like antigens and their roles in autoimmunity.
Professor Robert L. Byer has conducted research and taught classes in lasers and nonlinear optics at Stanford University since 1969. He has made numerous contributions to laser science and technology including the demonstration of the first tunable visible parametric oscillator, the development of the Q-switched unstable resonator Nd:YAG laser, remote sensing using tunable infrared sources and precision spectroscopy using Coherent Anti Stokes Raman Scattering (CARS). Current research includes the development of nonlinear optical materials and laser diode pumped solid state laser sources for applications to gravitational wave detection and to laser particle acceleration.
My lab addresses two distinct questions. That is, how can precise patterns of neuronal connections be genetically programmed during development, and how, once formed, can such circuits be used to mediate complex visual behaviors? Using the fruit fly visual system as a model, we employ genetic approaches to manipulate the functions of genes and neurons. From this, we infer specific developmental roles for particular molecules, and infer specific computational roles for individual neurons.
The Contag lab has developed microscope technology and molecular reagents for the noninvasive assessment of biological processes in vivo, and is applying these tools to the study of cellular and molecular changes associated with mammalian development, disease, and responses to therapy. Their technology allows the study of systems biology by measuring the complex physiologic events that are associated with disease states and normal developmental changes evaluated in the context of the living animals.
Professor Deisseroth’s research group focuses on developing molecular and cellular tools to observe, perturb, and reengineer brain circuits. His group is based in the James H. Clark Center at Stanford and uses a range of techniques including neural stem cell and tissue engineering methods, electrophysiology, molecular biology, neural activity imaging, animal behavior, and computational neural network modeling. Professor Deisseroth, who is also a clinician in the Department of Psychiatry, uses novel electromagnetic brain stimulation techniques in human patients for therapeutic purposes
The Digonnet group performs research on fiber optics. Previous areas of activity have included WDM fiber couplers, single crystal fibers, and integrated optics for fiber sensors. Current research interests include photonic-bandgap fibers, fiber sensors and sensor arrays, high-power ceramic lasers, fiber lasers and amplifiers, fiber gratings, slow light, and optical microcavities.